Table 1.
Characteristics of patients in TIMS‐China and original cohort that developed the THRIVE‐c score
| Characteristics | TIMS‐China (n = 1,128) | Original cohort (n = 6,194) | p |
|---|---|---|---|
| Female, n (%) | 440 (39.01) | 5,183 (42.5%) | <.001 |
| Age, years, median (IQR) | 64 (56–73) | 70 (60–76) | – |
| NIHSS, median (IQR) | 11 (7–16) | 12 (8–17) | – |
| CDS | 1 (0–1) | 1 (0–2) | – |
| Hypertension, n (%) | 667 (59.13) | 4,042 (66.1%) | <.001 |
| Diabetes Mellitus, n (%) | 196 (17.38) | 1,187 (19.3%) | .16 |
| Atrial Fibrillation, n (%) | 202 (17.91) | 1,504 (24.6%) | <.001 |
| Poor functional outcomea (3 months) | 462 (41.81) | 2,944 (50.3%) | <.001 |
| Mortality (3 months) | 115 (10.39) | – | |
| SICH (3 months) | 61 (5.41) | – | |
| THRIVE‐c, median (IQR) | 0.6148 (0.3492–0.7824) | – | |
| THRIVE, median (IQR) | 3 (2–4) | 3 (2–5) | – |
| SEDAN, median (IQR) | 1 (1–2) | – | |
| DRAGON, median (IQR) | 4 (3–5) | – | |
| HIAT2, median (IQR) | 2 (1–3) | – |
CDS, Chronic Disease Scale, 1 point each for presence of presence of HTN, DM, or AF; DRAGON, Dense Artery, Rankin Score, Age, Glucose, Onset to Treatment Time, HIAT2, Houston Intra‐Arterial Therapy 2 score; IQR, interquartile range; NIHSS; NIHSS indicates National Institutes of Health Stroke Scale; SEDAN, Sugar, Early Infarct Signs, Dense Artery, Age, NIH Stroke Score; SICH, symptomatic intracranial hemorrhage; THRIVE‐c, Totaled Health Risks in Vascular Events‐calculation; THRIVE, Totaled Health Risks in Vascular Events.
a
Poor functional outcome was defined as a modified Rankin Scale score of 3–6.