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. 2018 Jan 18;8(2):e00905. doi: 10.1002/brb3.905

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© 2018 The Authors. Brain and Behavior published by Wiley Periodicals, Inc.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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An intrahippocampal infusion of a low dose of propranolol‐induced PTSD‐like memory impairments. (a) Representative microphotograph depicting the injection site in the dHPC. (b) After a high‐intensity threat (1.4 mA), low doses of propranolol (1.25 or 5 μg) induced PTSD‐like memory impairments. ** p < .01, ^## p < .01 compared with the vehicle; ° p < .05, 5 μg versus 1.25 μg (n = 6 per group). (c) An intrahippocampal infusion of propranolol (1.25 or 5 μg) increased the response to the 2‐kHz tone, but not to white noise. ^## p < .01 compared with the 1‐kHz cue (n = 6 per group)