Table 3.
Observed and adjusted odds ratio of preeclampsia according to risk factors;17,738 singleton first or second deliveries. KCMC Medical birth registry July 2000-May 2013
| Maternal characteristics | No preeclampsia (n) | Preeclampsia [n (%)] |
Crude OR (95% CI) P-value |
Adjusted* OR (95% CI) P-value |
||
|---|---|---|---|---|---|---|
| Mother’s BMI (kg/m2) | < 0.001 | < 0.001 | ||||
| < 18.5 underweight | 1153 | 25 (2.1) | 0.7 (0.5-1.1) | 0.7 (0.4-1.1) | ||
| 18.5-24.9 normal | 10,694 | 314 (2.9) | Ref | Ref | ||
| 25.0-29.9 overweight | 4077 | 181 (4.3) | 1.5 (1.3-1.8) | 1.4 (1.2-1.8) | ||
| 30 thru highest obese | 1232 | 62 (4.8) | 1.7 (1.3-2.3) | 1.8 (1.3-2.4) | ||
| P for trend | < 0.001 | < 0.001 | ||||
| Mother’s age | < 0.001 | < 0.001 | ||||
| 13-19 | 2090 | 61 (2.8) | 1.1 (0.8-1.5) | 0.9 (0.7-1.3) | ||
| 20-24 | 6268 | 169 (2.6) | Ref | Ref | ||
| 25-29 | 5568 | 187 (3.2) | 1.2 (1.0-1.5) | 1.2 (1.0-1.5) | ||
| 30-34 | 2493 | 114 (4.4) | 1.7 (1.3-2.2) | 1.6 (1.2-2.1) | ||
| 35-50 | 706 | 49 (6.5) | 2.6 (1.9-3.6) | 2.6 (1.8-3.7) | ||
| P for trend | < 0.001 | < 0.001 | ||||
| Mother’s education | 0.08 | 0.4 | ||||
| None | 172 | 5 (2.8) | 0.8 (0.3-1.9) | 1.2 (0.5-3.1) | ||
| Primary | 8839 | 277 (3.0) | 0.8 (0.7-1.0) | 1.1 (0.9-1.5) | ||
| Secondary (8-11) | 1111 | 31 (2.7) | 0.7 (0.5-1.1) | 0.9 (0.6-1.3) | ||
| Higher (12+) | 7009 | 268 (3.7) | Ref | Ref | ||
| P for trend | 0.02 | 0.2 | ||||
| Pregnancy number | 0.06 | 0.001 | ||||
| First | 9992 | 362 (3.5) | Ref | Ref | ||
| Second | 7164 | 220 (3.0) | 0.8 (0.7-1.0) | 0.7 (0.6-0.9) | ||
| Marital status | 0.003 | 0.02 | ||||
| With partner | 14,348 | 459 (3.1) | Ref | Ref | ||
| Without partner | 2746 | 120 (4.2) | 0.7 (0.6-0.9) | 0.8 (0.6-1.3) | ||
| Mother’s occupation | < 0.001 | 0.07 | ||||
| Housewife | 3463 | 104 (2.9) | 1.0 (0.8-1.4) | 1.0 (0.8-1.4) | ||
| Farmer | 2704 | 80 (2.9) | Ref | Ref | ||
| Service | 1227 | 59 (4.6) | 1.6 (1.2-2.3) | 1.4 (1.0-2.0) | ||
| Business | 4012 | 113 (2.7) | 1.0 (0.7-1.3) | 0.8 (0.6-1.1) | ||
| Professional | 3629 | 161 (4.2) | 1.5 (1.1-2.0) | 1.2 (0.9-1.7) | ||
| Student | 573 | 19 (3.2) | 1.1 (0.7-1.9) | 1.1 (0.6-1.8) | ||
| Mother’s tribe | < 0.001 | < 0.001 | ||||
| Chagga | 9874 | 290 (2.9) | Ref | Ref | ||
| Pare | 1951 | 93 (4.5) | 1.6 (1.3-2.1) | 1.9 (1.4-2.4) | ||
| Others | 5531 | 199 (3.6) | 1.3 (1.1-1.5) | 1.5 (1.2-1.8) | ||
| Mother’s height | 0.009 | 0.01 | ||||
| < 155 cm | 4017 | 125 (3.0) | 0.7 (0.6-0.9) | 0.7 (0.6-1.0) | ||
| 155-164 cm | 9459 | 301 (3.1) | 0.8 (0.6-0.9) | 0.7 (0.6-0.9) | ||
| ≥ 165 cm | 3680 | 156 (4.1) | Ref | Ref | ||
| P for trend | 0.01 | 0.02 | ||||
*All variables are in the multivariable model