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. 2018 Feb 21;15:54. doi: 10.1186/s12974-018-1088-6

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Cytokine secretion of PHA-stimulated human PBL treated with PP-001. Cytokine secretion of PHA-stimulated human PBL from four donors with or without PP-001 (3 and 30 μM, respectively). Supernatants from triplicate cultures were collected at three time points (24, 48, and 72 h after onset of cultures, in total nine samples) and pooled for the final bioplex analysis. Cytokine secretion of cultures with PHA only is defined as 100%; the percentage of secretion in cultures with PP-001 is respectively calculated in relation to the PHA-control for each donor. Data show the means of % secretion from four different donors + SE, p values are only shown for significantly different data