Table 2.

Treatment at 3, 5 and 8 years from baseline (n (%))

	3 years n=625	5 years n=625	8 years n=454
Still on initial TNFi	385 (61)	292 (47)	150 (33)
Started a second TNFi within period	168 (27)	229 (37)	264 (42)
On second TNFi at time point	110 (18)	124 (20)	72 (16)
Started a third TNFi within period	39 (6)	62 (10)	96 (15)
On third or subsequent TNFi at time point	35 (6)	44 (7)	53 (12)
Started non-TNFi biologic within period	4 (0.6)	9 (1)	19 (3)
On other non-TNFi biologic treatment at time point	2 (0.3)	3 (0.5)	8 (2)
Not on biologic treatment	68 (11)	77 (12)	45 (10)
Died	10 (2)	23 (4)	34 (8)
Lost to follow-up	15 (2)	62 (10)	92 (20)