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. Author manuscript; available in PMC: 2018 Jul 15.
Published in final edited form as: Nat Chem. 2018 Jan 15;10(3):251–258. doi: 10.1038/nchem.2917

Figure 3. Logic-gated biomaterials exhibit programmable degradation in response to environmentally presented input combinations.

Figure 3

(a) The response profiles of the single-input YES-gated materials. The response profiles of the two-input (b) OR-gated materials and (c) AND-gated materials. The response profiles of the higher-order, three-input (d) OR/(AND)-, (e) AND/(OR)-, (f) OR/OR-, and (g) AND/AND-gated materials. Plot titles correspond to crosslinker identity, with x-axis labels indicating material treatment conditions (N is no treatment, E is MMP enzyme, R is a chemical reductant, P is UV light). Green bars signify conditions expected to result in material degradation; red bars indicate conditions expected not to yield material degradation. Error bars correspond to ± 1 standard deviation about the mean with propagated uncertainties for n = 3 experimental replicates.