Table 2.
Results of meta-analysis comparison of WZYZ pill and placebo or vitamin control.
| Outcome measures | Studies numbers | WZYZ pill participant numbers | Control participants numbers | MD (95% CI) | P value | Study heterogeneity | |||
|---|---|---|---|---|---|---|---|---|---|
| X 2 | df | I 2, % | P value | ||||||
| Sperm concentration | 5 | 509 | 451 | 5.99 [2.12, 9,85] | 0.002 | 79.74 | 4 | 95 | <0.00001 |
| Sperm mobility | 5 | 509 | 451 | 4.57 [0.47, 8.68] | 0.03 | 152.97 | 4 | 97 | <0.00001 |
| Sperm morphology | 2 | 66 | 56 | −1.93 [−4.87, 1.01] | 0.20 | 0.79 | 1 | 0 | 0.38 |
| Sperm DFI | 2 | 66 | 56 | −3.82 [−6.45, −1.19] | 0.004 | 0.18 | 1 | 0 | 0.67 |
| Activity of acrosomal enzyme | 2 | 109 | 81 | 28.27 [12.41, 44.14] | 0.0005 | 32.74 | 1 | 97 | <0.00001 |
| Sperm volume | 2 | 340 | 310 | 0.68 [0.64, 0.72] | <0.00001 | 2.69 | 1 | 63 | <0.1 |
WZYZ = Wuzi Yanzong; MD = mean difference; df = degree of freedom; CI = confidence interval; DFI = DNA fragmentation index.