Table 1.
Participant baseline demographic data
| Demographic parameters | NEM | Placebo |
|---|---|---|
| Age, years | 56.1±7.4 | 57.7±5.9 |
| Sex | ||
| Female (%) | 30 (100) | 30 (100) |
| Height, cm | 164±5 | 164±7 |
| Weight, kg | 75.7±13.6 | 78.1±14.5 |
| BMI, kg/m2 | 28.2±5.4 | 28.8±4.4 |
| uCTX-II, ng/mmol Cr | 258±106 | 236±175 |
| Resting pain score | 0.2±0.4 | 0.5±0.8 |
| Resting stiffness score | 0.3±0.6 | 0.6±0.9 |
| Number of steps per leg | 61.9±16.2 | 59.3±11.9 |
| Baseline pain score | 1.4±1.1 | 1.4±1.4 |
| Baseline stiffness score | 1.3±1.0 | 1.7±1.3 |
Notes: Except where indicated otherwise, values are reported as mean ± SD (n=30 per group). There were no statistical differences between treatment groups in any of the listed parameters. Baseline pain and stiffness scores were obtained from performing the number of steps per leg determined at screening.
Abbreviations: BMI, body mass index, calculated as weight in kilograms divided by the square of height in meters; NEM, natural eggshell membrane; uCTX-II, urinary C-terminal cross-linked telopeptide of type-II collagen, reported as nanograms per millimole of creatinine (ng/mmol Cr).