Figure 3.

Safranin O/Fast green stained methacrylate sagittal section of nucleotomised intervertebral discs treated with human mesenchymal stem cells in fibrin gel collected immediately (A) after completion of the last dynamic loading cycle and (B) following free swelling. Note the ability of fibrin to recover its initial shape following loading release. af = annulus fibrosus; ep = endplate; es = endplate stopper; f = fibrin gel with hMSCs; hMSCs = human mesenchymal stem cells; np = nucleus pulposus, Scale bar = 1 mm.