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Strategies to maximise innate regenerative capacity via stimulation of endogenous stem cell mobilisation. After tissue damage, stem cell-mobilising agent (e.g., G-CSF, SCF, SDF-1) is administered to further reinforce endogenous stem cell mobilization. Mobilised mesenchymal stem cells are recruited into damaged tissue via circulation, leading to accelerated recovery. G-CSF = granulocyte colony-stimulating factor; SCF = stem cell factor; SDF-1 = stromal cell-derived factor-1.
