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. 2017 May 25;10:42–51. doi: 10.1016/j.jot.2017.05.001

Figure 1.

Figure 1

GPR1−/− deficiency male mice have much lower bone mineral density. (A) MicroCT images of secondary spongy bone of the metaphysis of distal femora from GPR1−/− and WT control mice. (B) The quantitative microCT bone parameters BMD, BV/TV, Tb.Th, Tb.N, DA, SMI, Tb.Pf, and Tb.Sp. Statistical significance was assessed with two-tailed Student t test; **p < 0.01 versus WT, ***p < 0.001 versus WT, NWT = 15, NGPR1−/− = 6. BMD = bone mineral density; BV/TV = ratio of bone volume to tissue volume; DA = degree anisotropy; GPR1 = G protein-coupled receptor 1; microCT = microcomputed tomography; SMI = structure model index; Tb.N = trabecular number; Tb.Pf = trabecular pattern factor; Tb.Sp = trabecular separation; Tb.Th = trabecular thickness; WT = wild type.