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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Immunogenetics. 2017 Aug 7;70(3):179–183. doi: 10.1007/s00251-017-1022-6

Figure 2.

Figure 2

Single nucleotide polymorphism in β2-m signal peptide of rhesus macaque. A. C/G polymorphism reported in this study is shown in parentheses. The human β2-m signal peptide polymorphism associated with hypercatabolic hypoproteinemia (see text) is italicized. B. Confocal images showing similar golgi/ER targeting of GFP by constructs with either signal peptide (spC or spG). GFP was cloned downstream of the signal peptide as described in methods. C. Flowcytomtery histogram overlay shows similar GFP expression in 293T cells transfected with variant constructs. D. ELISA results for serum IgG and plasma β2m levels in animals with β2-m signal peptide GC or GG alleles.