Table 1. Anthropometric, clinical, and physical testing characteristics of the sample.
| Variable | HPS (n=42) | NHPS (n=48) | p value |
|---|---|---|---|
| Age, (years) | 60.4±7.10 | 58.7±8.20 | 0.9 |
| Height, (cm) | 167.7±6.4 | 169.5±7.1 | 0.8 |
| Weight, (kg) | 72.6±10.8 | 71.3±9.7 | 0.9 |
| MELD | 17.2±2.1 | 17.0±3.0 | 0.9 |
| Smoking, (n) | 6 | 9 | 0.8 |
| Mean pulmonary artery pressure, (mmHg) | 18.5±7.3 | 19.1±8.8 | 0.7 |
| International Normalized Ratio | 1.11±0.5 | 1.12±03 | 0.9 |
| 6MWT, (m) | 361.8±50.9 | 410.5±91.4 | 0.001 |
| VO2 peak, (mL/kg) | 15.3±2.1 | 17.3±2.6 | 0.001 |
| PImax, (cmH2O) | -55.1±9.8 | -74.2±13.9 | 0.01 |
| PEmax, (cmH2O) | 60.1±12.25 | 76.8±14.7 | 0.01 |
| Child Pugh Score B, (n) | 17 | 19 | 0.8 |
| Child Pugh Score C, (n) | 25 | 29 | 0.7 |
| Hepatitis C virus cirrhosis, (n) | 28 | 30 | 0.8 |
| Alcoholic cirrhosis, (n) | 14 | 18 | 0.8 |
| PaO2, (mmHg) | 67.9±9.3 | 89.1±10.1 | 0.01 |
| P(A-a)O2, (mmHg) | 22.9±1.72 | 13.4±1.65 | 0.01 |
| FVC, % of predicted | 95±17.4 | 97±15.3 | 0.7 |
| FEV1, % of predicted | 88±13.3 | 90±14.7 | 0.7 |
| FEV1/FVC | 0.77±0.03 | 0.78±0.05 | 0.8 |
HPS: patients with hepatopulmonary syndrome. NHPS: patients with no hepatopulmonary syndrome; MELD: Model for End Stage Liver Disease; 6MWT: six-minute walk test; VO2: oxygen consumption; PImax: maximum inspiratory pressure; PEmax: maximum expiratory pressure; PaO2: partial arterial oxygen pressure; P(A-a)O2: alveolar-arterial gradient for oxygen; FVC: forced vital capacity; FEV1: forced expiratory volume in the first second.