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. Author manuscript; available in PMC: 2018 Feb 22.
Published in final edited form as: Biochim Biophys Acta. 2017 Oct 12;1862(1):61–70. doi: 10.1016/j.bbagen.2017.10.006

Fig. 4. Influence of urolithin A on the mTOR signaling pathway in macrophages.

Fig. 4

Murine macrophages were treated with 20 and 40 μM urolithin A (Uro) in the presence and absence of LPS for 2 and 6 h. Cell lysates were prepared and subjected to western blot analysis for (a) phospho AKT (Thr308) and total AKT, for (b) phospho-TSC2 (Thr1462) and total TSC2, and (c) phospho-p70S6K (Ser389) and actin. Representative blots from three experiments and compiled densitometric data (target/loading control) are depicted (*, p < 0.05; vs LPS-treated solvent control).