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. Author manuscript; available in PMC: 2018 Feb 22.
Published in final edited form as: Cell Transplant. 2015 Jun 30;25(7):1371–1380. doi: 10.3727/096368915X688533

Figure 4.

Figure 4

Effects of optogenetic stimulation of NSC grafts on sensorimotor function. Three animal groups (n = 16) were used: vehicle, NSCs transduced with lenti-YFP, and NSCs transduced with lenti-ChR2. Each group was split into two subgroups: stimulated and nonstimulated. We used the cylinder test to measure forelimb use during spontaneous lateral exploration (A). Animals were also subjected to locomotor activity testing in the open field test during stimulation (B). Scale bars represent percentages ± SEM of steps taken by the ipsilateral (left), contralateral (right), and both forelimbs simultaneously. *p < 0.05 versus pretransplant groups; #p < 0.05 versus nonstimulated groups.