Appendix Figure 4.

CRC incidence expected in CF individuals according to Maisonneuve P. et al. 2013 and CRC incidence simulated in Microsimulation Screening Analysis-Colon model without screening in US general population, non-transplant, and transplant CF patients assuming higher CRC risk through a combination of a more frequent adenoma onset and a faster adenoma progression (sensitivity analysis).

Note: Bars indicate 95% CIs; CRC = colorectal cancer; CF = Cystic Fibrosis; B = Base case analysis; and S = Sensitivity analysis.