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. 2018 Mar;24(3):549–552. doi: 10.3201/eid2403.170772

Table. Characteristics of Nannizziopsis sp. infection in humans*.

Year (reference) Age, y/sex Country Underlying condition or context Species Localization Positive samples Treatment Outcome
2017 (this study)
52/F
France
HIV, living in Mali
Nannizziopsis sp.
Brain abscess
Cerebral biopsy, CSF
AmpB for 1 mo, then VCZ
Recovery but neurologic sequela after 2 mo
2015 (this study)
63/F
France
Leukemia, recent travel to Senegal
N. obscura
Brain abscess
Blood culture, CSF, ascites fluid
Not treated
(death before diagnosis)
Death before diagnosis
2005 (2)
38/M
Germany
HIV, travel to Nigeria
N. obscura
Brain abscess
Needle aspiration of brain lesion
VCZ
Recovery without sequelae after 4 mo
2005 (5)
40/M
United States
HIV
N. infrequens
Lung
Bronchial washing
Not treated,
considered as a contaminant
Recovery after treatment of CMV infection
2000 (3,4)
32/M
United States
Travel to Nigeria
N. hominis
Lymph nodes, heart, lungs, spleen, kidneys
3 lymph nodes
ITRA for 2 y
NA
1994 (3)
NA/M
United States
HIV
N. hominis
Right thigh mass
Deep muscle mass on the right thigh, right groin, buttock, and lung
ITRA
Death after 8 mo
1982 (1) 24/M United States Travel to Africa N. obscura Abscess in right ankle, osteomyelitis 2 biopsies of abscess in tibia AmpB for 4 mo Recovery after 4 mo

*AmpB, amphotericin B; CMV, cytomegalovirus; CSF, cerebrospinal fluid; ITRA, itraconazole; NA, not available; VCZ, voriconazole.