Table 2. Frequency of pfhrp2, pfhrp3, and flanking genes in patients infected with Plasmodium falciparum at 2 hospitals, Eritrea*.
| Hospital | Upstream | pfhrp2 | Downstream | No. (%) | Upstream | pfhrp3 | Downstream | No. (%) |
|---|---|---|---|---|---|---|---|---|
| Ghindae | + | + | + | 4 (15.4) | + | + | + | 2 (7.7) |
| + | – | – | 2 (7.7) | |||||
| – | + | + | 1 (3.9) | – | – | – | 1 (3.9) | |
| – | – | + | 21 (80.8) | – | – | – | 21 (80.8) | |
| Subtotal | 26 | 26 | ||||||
| Massawa | + | + | + | 7 (29.2) | + | + | + | 6 (25.0) |
| + | – | – | 1 (4.2) | |||||
| – | + | + | 7 (29.2) | + | + | + | 1 (4.2) | |
| + | – | – | 6 (25.0) | |||||
| – | – | + | 10 (41.7) | – | – | + | 2 (8.3) | |
| – | – | – | 8 (33.3) | |||||
| Subtotal | 24 | 24 | ||||||
| Combined | + | + | + | 11 (22.0) | + | + | + | 8 (16.0) |
| + | – | – | 3 (6.0) | |||||
| – | + | + | 8 (16.0) | + | + | + | 1 (2.0) | |
| + | – | – | 6 (12.0) | |||||
| – | – | – | 1 (2.0) | |||||
| – | – | + | 31 (62.0) | – | – | + | 2 (4.0) | |
| – | – | – | 29 (58.0) | |||||
| Total | 50 | 50 |
*Parasites with same presence or absence pattern for pfhrp2 and flanking genes but different presence or absence pattern for pfhrp3 and flanking genes are separated into subgroups. pfhrp, P. falciparum histidine-rich protein +, positive; –, negative.