Table 3. Performance of different parasitological and immunochromatographic methods for the detection of intestinal schistosomiasis in comparison with the reference standard (18 Kato-Katz slides, saline gradient, and Helmintex).
Method | Prevalence (%) | Sensitivity % (CI 95%) | Kappa Index (CI 95%) |
---|---|---|---|
SPL1 K1-K2 | 20.4 | 41.4 (32.8–50.5) | 0.42 (0.31–0.52) |
SLP1 K1-K6 | 29.0 | 56.4 (47.0–65.3) | 0.56 (0.44–0.67) |
SLP1 K1-K12 | 30.3 | 58.7 (49.3–67.5) | 0.58 (0.46–0.70) |
SLP1 K1-K14 | 29.9 | 58.2 (48.8–67.0) | 0.58 (0.46–0.70) |
SLP1-3 K1-K2 | 38.3 | 66.7 (57.3–74.9) | 0.63 (0.50–0.76) |
Saline Gradient | 21.3 | 44.7 (35.0–54.7) | 0.46 (0.34–0.58) |
Helmintex | 40.4 | 83.8 (75.6–89.6) | 0.84 (0.71–0.97) |
POC-CCA | 47.4 | 64.9 (55.6–73.1) | 0.34 (0.22–0.47) |
Data shows the prevalence, sensitivity, and kappa index of concordance for the Kato-Katz technique obtained with the analysis of one fecal sample using two (SPL1 K1-K2), six (SPL1 K1-K6), 12 (SPL1 K1-K12), and 14 slides (SPL1 K1-K14), or obtained from two slides prepared from each of three fecal samples (SPL1-3 K1-K2), or obtained with the saline gradient, Helmintex, or with POC-CCA methods.