Table 4. Sensitivity of different diagnostic methods for the detection of intestinal schistosomiasis considering the parasite load, as defined by egg counts of two Kato-Katz slides.
Classification by Parasite Load (EPG value) Sensitivity (%) of each diagnostic method | |||||
---|---|---|---|---|---|
Diagnostic Method | Heavy (EPG > 399) % Sensitivity |
Moderate (EPG: 100–399) % Sensitivity |
Light | ||
(EPG: 99–50) % Sensitivity |
(EPG: 49–12) % Sensitivity |
(EPG < 12) % Sensitivity |
|||
SPL1 K1-K2 | 100 (04/04) | 100 (12/12) | 100 (04/04) | 100 (28/28) | 0 (0/70) |
SPL1 K1-K6 | 100 (04/04) | 100 (12/12) | 100 (04/04) | 100 (28/28) | 22.6 (14/62) |
SPL1 K1-K12 | 100 (04/04) | 100 (11/11) | 100 (04/04) | 100 (28/28) | 27.4 (17/62) |
SPL1 K1-K14 | 100 (04/04) | 100 (11/11) | 100 (04/04) | 100 (28/28) | 27.0 (17/63) |
SPL1-3 K1-K2 | 100 (04/04) | 100 (12/12) | 100 (04/04) | 100 (28/28) | 40.0 (24/60) |
Saline Gradient | 100 (04/04) | 100 (06/06) | 33.3 (01/03) | 50.0 (11/22) | 33.9 (20/59) |
Helmintex | 100 (03/03) | 100 (11/11) | 75.0 (03/04) | 75.0 (18/24) | 84.1 (53/63) |
POC-CCA | 100 (04/04) | 100 (10/10) | 100 (04/04) | 77.8 (21/27) | 50.8 (34/67) |
Data show the sensitivity (%) of each diagnostic method and the number of individuals detected positive for intestinal schistosomiasis versus the total number of examined individuals (in brackets), according to parasite load classification. Individuals with a light infection were arbitrarily divided into three subgroups with egg counts of 99–50 eggs per gram of feces (EPG), 49–12 EPG, and less than 12 EPG.