(A) nfvPPA in a 66-year-old woman, MMSE: 28. Left predominant atrophy of the operculum is evident (arrow). (B) svPPA in a 66-year-old man with MMSE: 26. Atrophy is most prominent in the left perisylvian region, including the medial temporal lobes (arrow). Adapted with permission from Vitali P, Migliaccio R, Agosta F, Rosen H, Geschwind M. Neuroimaging in dementia. Semin Neurol 2008;28(4):467–483.