Table 4.
Top 10 SNPs in the Analysis of the BP Study in the NHLBI ESP
| SNP | MAF | Correlation
|
SMLE
|
MLE0
|
|||||
|---|---|---|---|---|---|---|---|---|---|
| log (BMI) | Race | Est | SE | p-value | Est | SE | p-value | ||
| 18:44595809 | 0.43 | 0.00 | 0.11 | 2.04E-01 | 4.63E-02 | 9.93E-06 | 2.05E-01 | 4.61E-02 | 8.37E-06 |
| 18:51904644 | 0.25 | 0.00 | −0.27 | 2.29E-01 | 5.63E-02 | 4.65E-05 | 2.14E-01 | 5.64E-02 | 1.47E-04 |
| 18:51904641 | 0.25 | −0.01 | −0.27 | 2.23E-01 | 5.62E-02 | 7.13E-05 | 2.09E-01 | 5.59E-02 | 1.86E-04 |
| 7:101713590 | 0.18 | 0.01 | −0.02 | 2.58E-01 | 6.59E-02 | 9.24E-05 | 2.17E-01 | 6.63E-02 | 1.06E-03 |
| 18:44585955 | 0.38 | −0.08 | −0.05 | 1.84E-01 | 4.81E-02 | 1.34E-04 | 1.89E-01 | 4.73E-02 | 6.54E-05 |
| 19:7166388 | 0.28 | 0.09 | 0.39 | 2.01E-01 | 5.39E-02 | 1.93E-04 | 1.79E-01 | 5.55E-02 | 1.29E-03 |
| 19:8176919 | 0.46 | 0.01 | −0.15 | −1.66E-01 | 4.47E-02 | 2.01E-04 | −1.62E-01 | 4.51E-02 | 3.29E-04 |
| 12:6464581 | 0.15 | 0.09 | 0.59 | 2.55E-01 | 7.00E-02 | 2.68E-04 | 2.43E-01 | 8.43E-02 | 3.93E-03 |
| 17:65720346 | 0.48 | −0.07 | −0.31 | −1.65E-01 | 4.59E-02 | 3.33E-04 | −1.48E-01 | 4.66E-02 | 1.49E-03 |
| 14:75590846 | 0.46 | 0.01 | −0.07 | 1.64E-01 | 4.58E-02 | 3.42E-04 | 1.52E-01 | 4.52E-02 | 7.42E-04 |
NOTE: SNP name is in the “chromosome:position” format, where the positions are based on the human reference sequence (UCSC Genome Browser, hg19). Est and SE stand for the genetic effect estimate and standard error, respectively. Correlation pertains to the SNP and covariate.