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. 2018 Jan 4;9(9):8512–8520. doi: 10.18632/oncotarget.23953

Table 1. Relationship between depth of tumor invasion and clinicopathological factors.

Factor Depth of tumor invasion P-value
pT1 (n = 138) pT2 (n = 17) pT3 (n = 55) pT4 (n = 37)
Sex
 Male 90 (65.2) 14 (82.3) 37 (67.3) 23 (62.2) 0.5045
 Female 48 (34.8) 3 (17.7) 18 (32.7) 14 (37.8)
Age (y)
 ≤ 70 72 (52.2) 11 (64.7) 29 (52.7) 25 (67.6) 0.3139
 >70 66 (47.8) 6 (35.3) 26 (47.3) 12 (32.4)
Lymph node metastasis
 Negative 114 (82.6) 8 (47.1) 14 (25.4) 7 (18.9) < 0.0001
 Positive 24 (17.4) 9 (52.9) 41 (74.6) 30 (81.1)
Stage
 I 130 (94.2) 9 (52.9) 0 (0.0) 0 (0.0) < 0.0001
 II-III 8 (5.8) 8 (47.1) 55 (100.0) 37 (0.0)
Lymphatic invasion
 Negative 112 (81.2) 6 (35.3) 10 (18.2) 3 (8.1) < 0.0001
 Positive 26 (18.8) 11 (64.7) 45 (81.8) 34 (91.9)
Venous invasion
 Negative 125 (90.6) 5 (29.4) 14 (25.4) 3 (8.1) < 0.0001
 Positive 13 (9.4) 12 (70.6) 41 (74.6) 34 (91.9)

pT1: invasion of lamina propria or submucosa; pT2: invasion of muscularis propria; pT3: invasion of subserosa; pT4: penetration of serosa or invasion of adjacent structures.