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. 2018 Jan 4;9(9):8512–8520. doi: 10.18632/oncotarget.23953

Table 2. Relationship between primary tumor score and clinicopathological factors.

Factor Primary tumor score P-value
0 (n = 109) 1 (n = 60) 2 (n = 78)
Sex
 Male 74 (67.9) 38 (63.3) 52 (66.7) 0.8337
 Female 35 (32.1) 22 (36.7) 26 (33.3)
Age (y)
 ≤ 70 60 (55.1) 31 (51.7) 46 (59.0) 0.6883
 >70 49(44.9) 29 (48.3) 32 (41.0)
Depth of tumor invasion
 pT1 109 (100.0) 29 (48.4) 0 (0.0) < 0.0001
 pT2 0 (0.0) 11 (18.3) 6 (7.7)
 pT3 0 (0.0) 17 (28.3) 38 (48.7)
 pT4 0 (0.0) 3 (5.0) 34 (43.6)
Lymph node metastasis
 Negative 92 (84.4) 35 (58.3) 16 (20.5) < 0.0001
 Positive 17 (15.6) 25 (41.7) 62 (79.5)
Stage
 I 105 (96.3) 31 (51.7) 3 (3.8) < 0.0001
 II-III 4 (3.7) 29 (48.3) 75 (96.2)
Lymphatic invasion
 Negative 91 (83.5) 29 (48.3) 11 (14.1) < 0.0001
 Positive 18 (16.5) 31 (51.7) 67 (85.9)
Venous invasion
 Negative 98 (89.9) 34 (56.7) 15 (19.2) < 0.0001
 Positive 11 (10.1) 26 (43.3) 63 (80.8)

pT1: invasion of lamina propria or submucosa; pT2: invasion of muscularis propria; pT3: invasion of subserosa; pT4: penetration of serosa or invasion of adjacent structures.