Table 2. Pooled analysis of the postoperative myocardial parameters and clinical outcomes.
| Endpoints | No. of Studies | RIC | Control | OR (95% CI) | SMD/WMD (95% CI) | P value |
|---|---|---|---|---|---|---|
| Enzyme level | 10 | 505 | 501 | / | -0.86 (-1.44, -0.28) | 0.004 |
| cSTR | 7 | 392 | 390 | 1.74 (1.09,2.77) | / | 0.020 |
| MSI | 3 | 163 | 155 | / | 0.09 (-0.04, 0.23) | 0.16 |
| Imaging IS | 4 | 259 | 268 | / | -1.62 (-4.6, 1.36) | 0.29 |
| ME | 4 | 193 | 191 | / | -1.19 ( -6.76, 4.39) | 0.68 |
| LVEF | 6 | 383 | 389 | / | 0.39 (-0.90, 1.67) | 0.56 |
| MACCE(overall) | 5 | 323 | 312 | 0.45 (0.27, 0.75) | / | 0.002 |
| < 1 year | 2 | 94 | 93 | 0.44 (0.12, 1.60) | / | 0.21 |
| ≥1year | 3 | 229 | 219 | 0.47 (0.25, 0.87) | / | 0.02 |
| All-cause mortality | 5 | 323 | 312 | 0.27 (0.12, 0.62) | / | 0.002 |
| < 1 year | 2 | 94 | 93 | 0.29 (0.04, 1.90) | / | 0.20 |
| ≥1year | 3 | 229 | 219 | 0.27 (0.11, 0.67) | / | 0.005 |
| Recurrent MI | 4 | 355 | 344 | 0.66 (0.29, 1.51) | / | 0.33 |
| TVR | 2 | 95 | 94 | 5.72 (0.65, 50.45) | / | 0.12 |
| Stent thrombosis | 1 | 48 | 48 | 0.32 (0.01, 8.05) | / | 0.49 |
| Stroke | 4 | 276 | 266 | 0.68 (0.21, 2.21) | / | 0.52 |
| HF | 3 | 354 | 353 | 0.57 (0.24, 1.34) | / | 0.20 |
Notes: cSTR, complete ST-segmental resolution; MSI, myocardial salvage index; ME, myocardial edema; LVEF, left ventricular ejection fraction; MACCE, major adverse cardiovascular and cerebrovascular event; MI, myocardial infarction; TVR, target vessel revascularization; HF, heart failure; OR, odds ratio; SMD, standardized mean difference; WMD, weighted mean difference; CI, confidence interval; RIC, remote ischemic conditioning.