Table 2. Amplification (AMPL) in candidate genes (MITF, EGFR, CCND1, cMET, and cKIT) among melanoma cell lines derived from primary and metastatic melanomas.
| Cell line | Tissue origin | MITF | EGFR | CCND1 | cMET | cKIT |
|---|---|---|---|---|---|---|
| GR-Mel | primary melanoma | Disomy | Disomy | AMPL | Disomy | Disomy |
| LCP-Mel | primary melanoma | Disomy | Disomy | Disomy | Disomy | Disomy |
| MNG-Mel | primary melanoma | Disomy | Disomy | Disomy | Disomy | Disomy |
| PNP-Mel | primary melanoma | Disomy | Disomy | Disomy | Disomy | Disomy |
| WM-115-4 | primary melanoma | Disomy | AMPL | AMPL | Disomy | Disomy |
| ST-Mel | primary melanoma | AMPL | Disomy | Disomy | Disomy | Disomy |
| UACC 62 | primary melanoma | Disomy | Disomy | Disomy | Disomy | Disomy |
| SBCL2 | primary melanoma | AMPL | AMPL | Disomy | Disomy | Disomy |
| COPA 159 | melanoma metastasis | AMPL | Disomy | Disomy | Disomy | Disomy |
| PE-MEL-41 | melanoma metastasis | AMPL | Disomy | Disomy | AMPL | Disomy |
| PE-MEL-43 | melanoma metastasis | AMPL | Disomy | Disomy | Disomy | Disomy |
| PE-MEL-47 | melanoma metastasis | AMPL | Disomy | AMPL | Disomy | Disomy |
| PNM-Mel | melanoma metastasis | Disomy | AMPL | Disomy | AMPL | Disomy |
| WM-266-4 | melanoma metastasis | AMPL | Disomy | Disomy | Disomy | AMPL |
| UACC 257 | melanoma metastasis | AMPL | AMPL | AMPL | Disomy | AMPL |
| ME 33797 | melanoma metastasis | AMPL | Disomy | Disomy | Disomy | Disomy |
| A375 | melanoma metastasis | Disomy | Disomy | Disomy | Disomy | Disomy |
| Mel3.0 | melanoma metastasis | AMPL | Disomy | Disomy | Disomy | Disomy |
| LB-24-Mel | melanoma metastasis | AMPL | AMPL | AMPL | AMPL | Disomy |
| PR-Mel | melanoma metastasis | AMPL | Disomy | Disomy | Disomy | Disomy |
| SN-Mel | melanoma metastasis | Disomy | AMPL | Disomy | Disomy | Disomy |
| MALME 37 | melanoma metastasis | Disomy | AMPL | Disomy | Disomy | Disomy |
| INT 9009 | melanoma metastasis | Disomy | AMPL | Disomy | Disomy | Disomy |
| M14 | melanoma metastasis | Disomy | Disomy | Disomy | Disomy | Disomy |
| 397-Mel | melanoma metastasis | AMPL | Disomy | Disomy | Disomy | Disomy |
| GL-Mel | melanoma metastasis | Disomy | Disomy | Disomy | Disomy | Disomy |
| CN-Mel | melanoma metastasis | Disomy | Disomy | Disomy | Disomy | Disomy |
| CR-Mel | melanoma metastasis | AMPL | Dysomy | AMPL | Disomy | Disomy |
| 13443-Mel | melanoma metastasis | Disomy | AMPL | Disomy | AMPL | AMPL |
| MAR-Mel | melanoma metastasis | AMPL | AMPL | AMPL | AMPL | Disomy |
| SK-Mel-28 | melanoma metastasis | AMPL | AMPL | AMPL | AMPL | AMPL |
| LCM-Mel | melanoma metastasis | Disomy | AMPL | Disomy | AMPL | Disomy |