Figure 1. RNA-Seq analysis of global transcriptome changes based on MCPIP1 expression.

(A) Principal component analysis (PCA) of RNA-Seq datasets and (B) Venn diagrams show the number of differentially expressed transcripts (adj. P-value < 0.05) in the MCPIP1 and D141N cells relative to the PURO cells (MCPIP1 vs. PURO and D141N vs. PURO datasets). PCA is based on the abundances of all transcripts detected in RNA-Seq analysis.