Figure 2. Expression level of PRDX1 is associated with poor prognosis of osteosarcoma patients.

(A and B) Representative images of PRDX1 IHC staining in osteosarcoma tissues. Expression level was scored base on IHC staining. Osteosarcoma patients dichotomized into low PRDX1 expression group (Score < 3; A) and high PRDX1 expression group (Score≥ 3; B). (C and D) Kaplan-Meier survival curves show that disease-free survival (DFS; left column) and overall survival (OS; right column) in training cohort. Log-rank test showed that osteosarcoma patients with high level of PRDX1 had significantly shorter DFS and OS than those with low level of PRDX1.