Table 2. Univariate and multivariate analysis of disease-free survival (dfs) and overall survival (os) in training cohort.

Variables		DFS				OS
		Univariate analysis		Multivariate analysis		Univariate analysis		Multivariate analysis
		HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
Tumor size (cm)	< 8 vs. > 8	2.041 (1.340–3.108)	0.001	1.831 (1.173–2.860)	0.008	2.115 (1.329–3.367)	0.002	1.723(1.045–2.841)	0.033
Histologic grade	Low vs. High	1.606 (1.051–2.455)	0.029	1.620(0.985–2.666)	0.058	1.669 (1.049–2.657)	0.031	1.788 (1.109–2.881)	0.017
TNM stage	I/II vs. III	2.446(1.599-3.740)	< 0.001	1.976(1.280-3.052)	0.002	2.139(1.341–3.412)	0.001	1.951(1.216-3.129)	0.006
PRDX1 expression	Low vs. High	2.114 (1.359–3.289)	0.001	1.845 (1.191–2.856)	0.006	1.951 (1.187–3.208)	0.008	1.938(1.197–3.138)	0.007