. 2016 Jul 28;9(9):8311–8325. doi: 10.18632/oncotarget.10882

Table 1. Five consistently replicated SNPs for model development in dataset2.

SNP	CHR.	Nearest gene	Region	Location on Chromosome^a	Non-risk	Risk	Dataset1					Dataset2
							Risk allele frequency			OR (95%CI)^b	P value^b	Risk allele frequency		OR (95% CI)^b	P value^b
							Cases	Controls		OR (95%CI)^b	P value^b	Cases	Controls	OR (95% CI)^b	P value^b
rs2736100	5	TERT	Intron	1339516	T	G	0.479		0.413	1.30(1.17-1.46)	3.96E-06	0.482	0.418	1.29(1.13-1.49)	2.69E-04
rs1077236	8	CCDC26	Intergenic	130709683	A	C	0.698		0.677	1.10(0.95-1.28)	0.219	0.725	0.688	1.20(1.03-1.39)	0.021
rs2157719	9	CCDKN2A/B	Intron	22023366	T	C	0.140		0.113	1.28(1.08-1.51)	4.19E-03	0.141	0.111	1.32(1.07-1.62)	9.23E-03
rs498872	11	PHLDB1	UTR-5	117982577	A	G	0.303		0.272	1.23(1.08-1.39)	1.19E-03	0.349	0.285	1.35(1.16-1.56)	7.81E-05
rs6010620	20	RTEL1	Intron	61780283	T	C	0.304		0.266	1.21(1.07-1.37)	2.39E-03	0.330	0.267	1.35(1.16-1.57)	9.25E-05

a, based on NCBI Build 36; b, Odds ratios (ORs), 95% confidence interval (95%CI) and P values were calculated from univariate logistic regression analyses based on additive model.