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. 2016 Jul 28;9(9):8311–8325. doi: 10.18632/oncotarget.10882

Table 2. Seven independent SNPs for model development in dataset3.

SNP CHR Nearest gene Region Location on
Chromosomea
Non-risk Risk Risk allele frequency OR (95%CI)b P valueb
Cases Controls
rs2853677 5 TERT Intron 1287194 T C 0.449 0.375 1.36(1.20-1.55) 2.70E-06
rs2735948 5 TERT Intergenic 1299213 C T 0.170 0.146 1.20(1.01-1.42) 0.044
rs6589664 11 TMEM25 Exon 117910014 G A 0.310 0.271 1.21(1.05-1.39) 6.80E-03
rs494560 11 PHLDB1 Intron 118026759 A G 0.801 0.746 0.73(1.18-1.60) 4.04E-05
rs17748 11 PHLDB1 UTR-3 118033634 C T 0.327 0.263 1.36(1.18-1.56) 1.57E-05
rs3761121 20 ZGPAT Intron 62342695 A G 0.269 0.202 1.45(1.25-1.69) 9.85E-07
rs1058319 20 SLC2A4RG UTR-3 62374389 T C 0.354 0.256 1.59(1.39-1.83) 4.76E-11

a, based on NCBI Build 36; b, ORs, 95%CI and P values were calculated from univariate logistic regression analysis based on additive model.