Skip to main content
. 2018 Jan 2;9(10):8927–8940. doi: 10.18632/oncotarget.23826

Figure 2. Let-7c inhibits IGF1R and HMGA2 expression in HNSCC cell lines.

Figure 2

HNSCC cells were stably transfected with either pCMV-MIR vector or pCMV-MIR-let-7c vector. Expression levels of (A, B) let-7c and (C, D) IGF1R and HMGA2 mRNA were examined in HNSCC cell lines SAS and Ca9-22, respectively, with RT-qPCR. (E, F) IGF1R and HMGA2 protein levels were examined by western blot analysis in stably transfected let-7-expressing SAS and Ca9-22 cell lines, respectively, with GAPDH serving as loading control. P-values were calculated using the Student’s t-test. ***P < 0.001.