Table 3. Summary of the public datasets used in this study.

	Author & Year	No. of samples (total/normal)	Source & Notes
CNAs:	Chitale et al., 2009 [93]	199	http://cbio.mskcc.org/public/
	Job et al., 2010 [97]	60	E-TABM-926, ArrayExpress
Gene expression:	Bhattacharjee et al., 2001 [98]	207/17	http://www.broadinstitute.org/MPR/lung/
	Beer et al., 2002 [99]	96/10	GSE68571
	Stearman et al., 2005 [100]	39/19	GSE2514
	Yap et al., 2005 [101]	58/9	E-MEXP-231, ArrayExpress
	Su et al., 2007 [102]	54/27	GSE7670
	Landi et al., 2008 [103]	107/50	GSE10072
	Rohrbeck et al., 2008 [85]	15/5	GSE6044
	Hou et al., 2010 [86]	109/64	GSE19188
	Girard et al., 2011	50/20	GSE31547, Unpublished
	Okayama et al., 2012 [25]	246/20	GSE31210
miRNA expression:	Yanaihara et al., 2006 [87]	208/104
	Cho et al., 2009 [88]	20/10
	Crawford et al., 2009 [89]	20/8
	Dacic et al., 2010 [90]	12/6
	Yu et al., 2010 [91]	40/20
	Lee et al., 2011 [92]	12/6
	Jang et al., 2012 [94]	206/103
	Ma et al., 2014 [95]	108/54
	Nadal et al., 2014 [96]	101/10