Table 1. Patients characteristics.
Characteristics | No. of patients (%) | |
---|---|---|
N | 71 | |
Age (years) | Mean ± SD | 53.7 ± 13.7 |
≤45 | 22 (31.0) | |
46–55 | 18 (25.4) | |
56–65 | 15 (21.1) | |
≥ 66 | 16 (22.5) | |
PS | 0 | 13 (18.3) |
1 | 41 (57.7) | |
2 | 14 (19.7) | |
3 | 3 (4.2) | |
Follow-up time (months) | Median | 19.9 |
Mean ± SD | 34.2 ± 38.4 | |
Range | 1.9 - 177.4 | |
Tumor characteristics | Maximum tumor diameter (mm): mean ± SD | 67.0 ± 21.4 |
Tumor volume (cc) | 112.71 ± 97.47 | |
Invasion of bladder | Histologically proven | 15 (21.1) |
Cystoscopy | 13 (18.3) | |
Laparoscopy | 1 (1.4) | |
MRI | 39 (54.9) | |
CT scan | 3 (4.2) | |
Invasion of rectum | 13 (18.3) | |
Fistula at diagnosis | Bladder | 8 (11.3) |
Rectum | 1 (1.4) | |
Parametrial invasion | Unilateral | 8 (11.3) |
Bilateral | 61 (85.9) | |
No | 2 (2.8) | |
Clinical distal parametrial involvement | 45 (63.4) | |
Vaginal invasion | Yes | 55 (77.5) |
Limited to the upper two-third | 36 (50.7) | |
Lower third involvement | 19 (26.8) | |
Hydronephrosis | Unilateral | 37 (52.1) |
Bilateral | 20 (28.2) | |
No | 14 (19.7) | |
Stage (FIGO) | IV A | 48 (67.6) |
IV B | 23 (32.4) | |
Nodal involvement | No | 24 (33.8) |
Pelvic nodes only | 26 (36.6) | |
Para-aortic nodes only | 5 (7.0) | |
Both pelvic and para-aortic | 16 (22.5) | |
PALN involvement | CT scan | 3 (4.2) |
MRI | 9 (12.7) | |
PET | 8 (11.3) | |
PALN dissection | 1 (1.4) | |
Metastasis at diagnosis | Ovarian | 2 (2.8) |
Peritoneal | 1 (1.4) | |
Dorsal vertebra | 1 (1.4) | |
Supraclavicular node | 1 (1.4) | |
Para-aortic nodes laparoscopic staging | Positive | 1 (1.4) |
Negative | 11 (15.5) | |
Histology | Squamous cell carcinoma | 61 (85.9) |
Adenocarcinoma | 8 (11.3) | |
Other | 2 (2.8) | |
Differentiation | Low | 21 (29.6) |
Moderate | 20 (28.2) | |
High | 19 (26.8) | |
Unknown | 11 (15.5) |
Abbreviations: SD: standard deviation; FIGO: International Federation of Gynecology, Obstetrics; CT: computed Tomography; MRI: magnetic resonance imaging. PALN: para-aortic lymph nodes.