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. 2018 Jan 18;9(10):9299–9310. doi: 10.18632/oncotarget.24271

Table 2. Characteristics of treatment.

Characteristics No. of patients (%)
Chemotherapy Neoadjuvant CT only 3 (4.2)
cCRT 47 (66.2)
Neoadjuvant + cCRT 7 (9.9)
No CT 14 (19.7)
Number of cCRT cycles ≤ 4 40 (56.3)
≥ 5 24 (33.8)
Unknown 7 (9.9)
Radiotherapy: technique 2DCRT 19 (26.8)
3DCRT 35 (49.3)
IMRT 5 (7.0)
Not detailed 12 (16.9)
Radiotherapy: fields Pelvic 48 (67.6)
Pelvic + paraaortic 23 (32.4)
Sequential radiation boost Parametrium 12 (16.9)
Pelvic nodes 18 (25.4)
Para-aortic nodes 9 (12.7)
Brachytherapy LDR 33 (46.5)
PDR 31 (43.7)
No BT 7 (10)
OTT (from the start of RT to the end of BT, n = 64) ≤ 55 days 38 (59.4)
> 55 days 26 (40.6)
Median (range) 54 days (42–143)
Dosimetric Parameters Mean ± SD N available
Radiotherapy Pelvic dose 44.7 ± 3.1 71
Brachytherapy Points A dose (Gyα/β10) 71.1 ± 9.2 45
TRAK (cGy.h−1.m−1) 2.0 ± 0.4 64
V15Gyα/β3 (cm3) 270.2 ± 78.70 63
HR-CTV Volume (cm3) 48.9 ± 27.6 31
D90 (Gyα/β10) 72.6 ± 9.7 30
IR-CTV Volume (cm3) 108.5 ± 50.6 31
D90 (Gyα/β10) 63.1 ± 5.0 30
Bladder D2cc (Gyα/β3) 74.7 ± 6.5 30
ICRU (Gyα/β3) 72.0 ± 13.0 57
Rectum D2cc (Gyα/β3) 66.1 ± 5.9 30
ICRU (Gyα/β3) 74.5 ± 13.9 58
Sigmoid D2cc (Gyα/β3) 57.8 ± 6.7 30

Abbreviations: cCRT: concurrent chemoradiation; TRAK: total reference air kerma; ICRU: International Commission Radiation Units: HR-CTV: high-risk clinical target volume; IR: intermediate-risk clinical target volume: OTT: overall treatment time; RT: radiation therapy; LDR: low dose rate; PDR: pulse dose rate; BT: brachytherapy.