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(A) 100 nM Mimic-1 reduces CSCs viability by 80% while 100 μM 5-FU has minimal effect. (B) Mimic-1 reduces the expression of targets E2F3 and BCL2 in colon CSCs. (C) Mimic-1 can inhibit proliferation of colon CSCs. (D) Mimic-1 inhibits sphere formation in colon CSCs. (E) Mimic-1 induces apoptosis in colon CSCs. (**p<0.01; ***p<0.001).
