Table 1. Baseline demographic and tumor characteristics of SEER database patients.
| Total | Married | Widowed | Never married | Divorced/ Separated |
P | |
|---|---|---|---|---|---|---|
| Characteristic | (n = 24035) | (n = 13268) | (n = 5062) | (n = 3347) | (n = 2358) | |
| N | N (%) | N (%) | N (%) | N (%) | ||
| Sex | < 0.001 | |||||
| Male | 10774 | 7396 (55.7) | 898 (17.7) | 1530 (45.7) | 950 (40.3) | |
| Female | 13261 | 5872 (44.3) | 4164 (82.3) | 1817 (54.3) | 1408 (59.7) | |
| Age | < 0.001 | |||||
| ≤ 60 | 6314 | 3866 (29.1) | 210 (4.1) | 1452 (43.4) | 786 (33.3) | |
| > 60 | 17721 | 9402 (70.9) | 4852 (95.9) | 1895 (56.6) | 1572 (66.7) | |
| Race | < 0.001 | |||||
| White | 18478 | 10302 (77.6) | 3935 (76.4) | 2405 (73.8) | 1836 (77.9) | |
| Black | 2270 | 886 (6.7) | 579 (11.2) | 489 (15.0) | 316 (13.4) | |
| Other* | 3287 | 2080 (15.7) | 638 (12.4) | 363 (11.1) | 206 (8.7) | |
| Tumor site | < 0.001 | |||||
| Gallbladder | 7869 | 4014 (30.3) | 1938 (38.3) | 1120 (33.5) | 797 (33.8) | |
| Bile duct | 12668 | 7176 (54.1) | 2503 (49.4) | 1748 (52.2) | 1241 (52.6) | |
| Ampulla of Vater | 3498 | 2078 (15.7) | 621 (12.3) | 479 (14.3) | 320 (13.6) | |
| AJCC 6th TNM stage | < 0.001 | |||||
| I | 5205 | 2842 (22.2) | 1224 (22.0) | 675 (20.2) | 464 (19.7) | |
| II | 5109 | 2974 (23.3) | 938 (16.9) | 690 (20.6) | 507 (21.5) | |
| III | 2715 | 1627 (12.7) | 432 (7.8) | 356 (10.6) | 300 (12.7) | |
| IV | 7521 | 4239 (33.2) | 1373 (24.7) | 1117 (33.4) | 792 (33.6) | |
| Unknown | 3485 | 1095 (8.6) | 1586 (28.6) | 509 (15.2) | 295 (12.5) | |
| Grade | < 0.001 | |||||
| I | 1702 | 985 (7.4) | 334 (6.6) | 237 (7.1) | 146 (6.2) | |
| II | 5891 | 3443 (25.9) | 1059 (20.9) | 819 (24.5) | 570 (24.2) | |
| III | 5139 | 3006 (22.7) | 943 (18.6) | 682 (20.4) | 508 (21.5) | |
| IV | 220 | 125 (0.9) | 52 (1.0) | 26 (0.8) | 17 (0.7) | |
| Unknown | 11083 | 5709 (43.0) | 2674 (52.8) | 1583 (47.3) | 1117 (47.4) | |
| SEER Stage | < 0.001 | |||||
| Localized | 5526 | 2870 (21.6) | 1390 (27.5) | 757 (22.6) | 509 (21.6) | |
| Regional | 7853 | 4680 (35.3) | 1370 (27.1) | 1051 (31.4) | 752 (31.9) | |
| Distant | 8367 | 4743 (35.7) | 1504 (29.7) | 1227 (36.7) | 893 (37.9) | |
| Unknown | 2289 | 975 (7.3) | 798 (15.8) | 312 (9.3) | 204 (8.7) | |
| Therapy | < 0.001 | |||||
| Surgery | 10169 | 6046 (45.6) | 1788 (35.3) | 1353 (40.4) | 982 (41.6) | |
| No surgery | 13629 | 7107 (53.6) | 3207 (63.4) | 1962 (58.6) | 1353 (57.4) | |
| Unknown | 237 | 115 (0.9) | 67 (1.3) | 32 (1.0) | 23 (1.0) |
*: Other includes American Indian/Alaska native, Asian/Pacific Islander, and unknown.