Table 3. Top disease and functional categories of differentially expressed miRNAs in the VAT/BAT comparison of HFD fed mice.
| Diseases or functions annotation | p-Value | Activation z-score | Number of molecules |
|---|---|---|---|
| Cellular growth and proliferation | |||
| Proliferation of cells | 1.04E-03 | −0.736 | 38 |
| Cell proliferation of tumor cell lines | 2.77E-11 | −0.549 | 34 |
| Cell death and survival | |||
| Necrosis | 1.85E-02 | 1.273 | 25 |
| Cell death of tumor cell lines | 2.95E-02 | 1.421 | 16 |
| Cancer, organismal injury and abnormalities | |||
| Advanced malignant tumor | 1.72E-06 | 0.447 | 19 |
| Neoplasia of cells | 4.53E-07 | 1.191 | 43 |
| Metastasis | 1.60E-06 | 0.447 | 18 |
| Cellular movement | |||
| Cell movement of tumor cell lines | 4.37E-06 | 0.776 | 18 |
| Migration of tumor cell lines | 1.38E-06 | 1.466 | 17 |
| Invasion of tumor cell lines | 4.57E-07 | 0.157 | 17 |
P value < 0.05 is significant.