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. 2017 Dec 19;9(10):8957–8971. doi: 10.18632/oncotarget.23420

Figure 4. GSTP1 overexpression decreased liver cancer cell proliferation in vitro and in vivo.

Figure 4

(A) CCK8 assay showed that GSTP1-transfected liver cancer cells had decreased cell viability than in control. (B) Colony size and density in GSTP1 overexpression groups were smaller and rarer than that in control groups. (C) In the xenograft assay, tumor volume and weight were lower in mice over-expressing GSTP1. (D) When compared to control groups, GSTP1 overexpression led to an accumulation of cells in G1 phase and a decrease of cells in S phase. Data were mean ± SD of three biological replicates (*P < 0.05, **P < 0.01).