Table 1. Correlation between GSTP1 and clinicopathologic features in 237 HCC patients.
| Variable (missing cases) | Cases | GSTP1 | P-value | |||
|---|---|---|---|---|---|---|
| - | + | ++ | +++ | |||
| Gender | 0.529 | |||||
| Female | 24(10.1%) | 1(4.2%) | 7(29.1%) | 10(41.7%) | 6(25%) | |
| Male | 213(89.9%) | 25(11.7%) | 52(24.5%) | 92(43.2%) | 44(21.6%) | |
| Age | 0.07 | |||||
| ≤ 50 ys | 112(47.3%) | 16(14.2%) | 30(26.8%) | 46(41.1%) | 20(17.9%) | |
| >50 ys | 125(52.7%) | 10(8%) | 29(23.2%) | 56(44.8%) | 30(24%) | |
| HBsAg (3) | 0.217 | |||||
| Negative | 37(15.8%) | 4(10.8%) | 7(18.9%) | 15(40.6%) | 11(29.7%) | |
| Positive | 197(84.2%) | 22(11.2%) | 52(26.4%) | 85(43.1%) | 38(19.3%) | |
| Preoperative serum AFP (2) | 0.003** | |||||
| ≤ 400 ng/ml | 78(32.8%) | 2(2.6%) | 20(25.6%) | 32(41%) | 24(30.8%) | |
| >400 ng/ml | 157(67.2%) | 24(15.4%) | 39(24.8%) | 69(43.9%) | 25(15.9%) | |
| Tumor Number | 0.639 | |||||
| Single | 185(78.1%) | 20(10.8%) | 47(25.4%) | 81(43.8%) | 37(20%) | |
| Multiple | 52(21.9%) | 6(11.5%) | 12(23.1%) | 21(40.4%) | 13(25%) | |
| Tumor size | 0.013* | |||||
| ≤ 3 cm | 50(21%) | 3(6%) | 10(20%) | 23(46%) | 14(28%) | |
| 3-5 cm | 59(25%) | 5(8.6%) | 14(23.7%) | 25(42.3%) | 15(25.4%) | |
| > 5 cm | 128(54%) | 18(14.1%) | 35(27.3%) | 54(42.2%) | 21(16.4%) | |
| Edmondson-Steiner grade | 0.475 | |||||
| I | 2(0.8%) | 0(0%) | 0(0%) | 1(50%) | 1(50%) | |
| II | 17(7.2%) | 0(0%) | 6(35.3%) | 9(52.9%) | 2(11.8%) | |
| III-IV | 218(92%) | 26(11.9%) | 53(24.3%) | 92(42.2%) | 47(21.6%) | |
| PVTT | 0.299 | |||||
| Absent | 87(36.7%) | 7(8.1%) | 19(21.8%) | 43(49.4%) | 18(20.7%) | |
| Present | 150(63.3%) | 19(12.7%) | 40(26.7%) | 59(39.3%) | 32(21.3%) | |
| Liver cirrhosis | 0.744 | |||||
| No | 80(33.6%) | 7(8.8%) | 18(22.4%) | 41(51.3%) | 14(17.5%) | |
| Yes | 157(66.4%) | 19(12.1%) | 41(26.1%) | 61(38.9%) | 36(22.9%) | |
| TNM | 0.462 | |||||
| I | 75(31.5%) | 7(9.3%) | 15(20%) | 39(52%) | 14(18.7%) | |
| II | 130(55.1%) | 14(10.8%) | 36(27.7%) | 51(39.2%) | 29(22.3%) | |
| III-IV | 32(13.4%) | 5(15.6%) | 8(25%) | 12(37.5%) | 7(21.9%) | |
*
P<0.05, **P<0.01, have statistical significance.