Figure 5. Induction of apoptosis of three CRC cells by PRMT6 knockdown.

(A) Quantification of the mean annexin-V and propidium iodide fluorescence in early and late apoptotic cell populations with three independent experiments. Representative scatter plots of each cell lines are presented in Supplementary Figure 3. ^*, p < 0.05; ^**, p < 0.01. (B) Induction of cleaved forms of caspase 3 and PARP proteins in PRMT6-suppressed CRC cells.