Table 1. The association of the expression of PRMT6 (negative/positive) with the clinicopathologic variables.
| PRMT6 | p-value | ||
|---|---|---|---|
| Negative (N = 447) | Positive (N = 139) | ||
| Gender | |||
| Female | 169 (37.8) | 52 (37.4) | 0.933 |
| Male | 278 (62.2) | 87 (62.6) | |
| Location | |||
| Colon | 327 (73.2) | 109 (78.4) | 0.214 |
| Rectum | 120 (26.8) | 30 (21.6) | |
| CEA level | |||
| ≤ 5 ng/ml | 362 (81.0) | 116 (83.5) | 0.512 |
| > 5 ng/ml | 85 (19.0) | 23 (16.5) | |
| T stage | |||
| T1-2 | 35 (7.8) | 5 (3.6) | 0.084 |
| T3-4 | 412 (92.2) | 134 (96.4) | |
| N stage | |||
| N0 | 230 (51.5) | 78 (56.1) | 0.336 |
| N+ | 217 (48.5) | 61 (43.9) | |
| Cell type | |||
| WD/MD | 415 (92.8) | 117 (84.2) | 0.002 |
| PD/Muc/SRC | 32 (7.2) | 22 (15.8) | |
| Lymphatic invasion | |||
| Negative | 328 (73.4) | 102 (73.4) | 0.999 |
| Positive | 119 (26.6) | 37 (26.6) | |
| Vascular invasion | |||
| Negative | 390 (87.2) | 114 (82.0) | 0.120 |
| Positive | 57 (12.8) | 25 (18.0) | |
| Perineural invasion | |||
| Negative | 413 (92.4) | 130 (93.5) | 0.655 |
| Positive | 34 (7.6) | 9 (6.5) | |
| Adjuvant chemotherapy | |||
| Yes | 353 (79.0) | 105 (75.5) | 0.637 |
| No | 34 (7.6) | 11 (7.9) | |
| Undescribed | 60 (13.4) | 23 (16.5) | |