Skip to main content
. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Jan 11;38(3):500–508. doi: 10.1161/ATVBAHA.117.310345

Figure 5.

Figure 5

Fn-EDA promotes MMP-cleaved aggrecan accumulation in advanced plaques. A, Representative immunofluorescence images of sections from 1-year old mice stained with anti-aggrecan antibody. B, Quantification of MMP-cleaved aggrecan-positive area. Data represent mean ± SEM. N=7–8 mice/group. Value for each mouse represents a mean from 4 serial sections (each section approximately 60 μm apart). *P<0.05 versus Apoe−/− mice. Statistical analysis: Kruskal-Wallis test followed by uncorrected Dunn’s test. Scale bar= 50 μm.