Table 1.
Baseline Demographic and Clinical Variables
| Variable | IPSRT + QUETIAPINE (N = 47) | IPSRT + PLACEBO (N = 45) | P |
|---|---|---|---|
| Gender (n, % male) | 15 (31.9%) | 19 (42.2%) | 0.31 |
| Age (mean±SD) | 30.9±10.3 | 33.9±11.2 | 0.18 |
| Ethnicity (n, %Hispanic) | 1 (2.1%) | 2 (4.4%) | 0.53 |
| Race | |||
| N, % Caucasian | 31 (66.0%) | 35 (77.8%) | |
| N, % African American | 10 (21.3%) | 6 (13.3%) | |
| N, % other | 6 (12.7%) | 4 (8.9%) | |
| Marital Status | 0.80 | ||
| Never Married | 30 (63.8%) | 27 (60%) | |
| Married/Living as Married | 11 (23.4%) | 10 (22.2%) | |
| Separated/Divorced/Widowed | 6 (12.8%) | 8 (17.8%) | |
| Education (highest level attained) | 0.11 | ||
| High School Degree or Less | 4 (8.5%) | 9 (20%) | |
| Some college or Associates Degree | 26 (55.3%) | 22 (48.9%) | |
| Bachelor’s Degree | 11 (23.4%) | 13 (28.9%) | |
| Graduate or Professional Degree | 6 (12.8%) | 1 (2.2%) | |
| Total Income per Year | 0.19 | ||
| <$30,000 | 27 (57.4%) | 21 (46.7%) | |
| $30,000-$74,999 | 19 (40.4%) | 19 (42.2%) | |
| ≥$75,000 | 1 (2.1%) | 5 (11.1%) | |
| Psychotropic medication prior to entering study | 6 (12.8%) | 11 (24.4%) | 0.15 |
| Duration of current depressive episode (weeks) (median with Interquartile range) | 17 (8-114.5) | 17 (8-82-7) | 0.48 |
| Lifetime Diagnosis of Anxiety – DSM IV (%) | 31 (66%) | 29 (64.4%) | 0.88 |
| Current Diagnosis of Anxiety – DSM IV (%) | 28 (59.6%) | 26 (57.8%) | 0.86 |
| # Lifetime Episodes of Depression (median) | 3 | 6 | 0.07 |
| # Lifetime Episodes of Hypomania (median) | 6 | 12 | 0.05 |
| Hamilton Rating Scale for Depression – 17 Item (mean±SD) | 19.6±3.9 | 21.0±4.6 | 0.12 |
| Hamilton Rating Scale for Depression – 25 Item (mean±SD) | 24.7±4.9 | 26.0±5.4 | 0.24 |
| Young Mania Rating Scale (mean±SD) | 6.2±3.5 | 6.2±3.4 | 0.96 |
| BMI (mean±SD) | 27.6±8.0 | 26.4±5.7 | 0.53 |