Table 2.
Percentage of participants experiencing self-reported side effects on the Patient Rated Inventory of Side Effects (PRISE)
| treatment assignment | ||||||
|---|---|---|---|---|---|---|
| IPSRT+placebo (N=38) | IPSRT+quetiapine (N=42) | |||||
| N | % | N | % | χ2-test, p-value | ||
| Diarrhea | no | 21 | 55.3% | 22 | 52.4% | .796 |
| yes | 17 | 44.7% | 20 | 47.6% | ||
| Constipation | no | 24 | 63.2% | 18 | 42.9% | .069 |
| yes | 14 | 36.8% | 24 | 57.1% | ||
| Dry mouth | no | 16 | 42.1% | 9 | 21.4% | .046 |
| yes | 22 | 57.9% | 33 | 78.6% | ||
| Nausea/vomiting | no | 16 | 42.1% | 18 | 42.9% | .946 |
| yes | 22 | 57.9% | 24 | 57.1% | ||
| Palpitations | no | 20 | 52.6% | 20 | 47.6% | .654 |
| yes | 18 | 47.4% | 22 | 52.4% | ||
| Dizziness on standing | no | 17 | 44.7% | 17 | 40.5% | .700 |
| yes | 21 | 55.3% | 25 | 59.5% | ||
| Chest pain | no | 23 | 60.5% | 28 | 66.7% | .568 |
| yes | 15 | 39.5% | 14 | 33.3% | ||
| Rash | no | 28 | 73.7% | 36 | 85.7% | .179 |
| yes | 10 | 26.3% | 6 | 14.3% | ||
| Increased perspiration | no | 23 | 60.5% | 28 | 66.7% | .568 |
| yes | 15 | 39.5% | 14 | 33.3% | ||
| Itching | no | 20 | 52.6% | 24 | 57.1% | .685 |
| yes | 18 | 47.4% | 18 | 42.9% | ||
| Dry skin | no | 15 | 39.5% | 13 | 31.0% | .425 |
| yes | 23 | 60.5% | 29 | 69.0% | ||
| Headache | no | 5 | 13.2% | 6 | 14.3% | .884 |
| yes | 33 | 86.8% | 36 | 85.7% | ||
| Tremors | no | 27 | 71.1% | 30 | 71.4% | .970 |
| yes | 11 | 28.9% | 12 | 28.6% | ||
| Poor coordination | no | 21 | 55.3% | 16 | 38.1% | .124 |
| yes | 17 | 44.7% | 26 | 61.9% | ||
| Dizziness | no | 19 | 50.0% | 16 | 38.1% | .284 |
| yes | 19 | 50.0% | 26 | 61.9% | ||
| Blurred vision | no | 24 | 63.2% | 22 | 52.4% | .330 |
| yes | 14 | 36.8% | 20 | 47.6% | ||
| Ringing in ears | no | 28 | 73.7% | 24 | 57.1% | .121 |
| yes | 10 | 26.3% | 18 | 42.9% | ||
| Difficulty urinating | no | 31 | 81.6% | 36 | 85.7% | .617 |
| yes | 7 | 18.4% | 6 | 14.3% | ||
| Painful urination | no | 36 | 94.7% | 35 | 83.3% | .107 |
| yes | 2 | 5.3% | 7 | 16.7% | ||
| Frequent urination | no | 22 | 57.9% | 21 | 50.0% | .479 |
| yes | 16 | 42.1% | 21 | 50.0% | ||
| Menstrual irregularity | no | 31 | 81.6% | 30 | 71.4% | .287 |
| yes | 7 | 18.4% | 12 | 28.6% | ||
| Difficulty sleeping | no | 5 | 13.2% | 9 | 21.4% | .331 |
| yes | 33 | 86.8% | 33 | 78.6% | ||
| Sleeping too much | no | 9 | 23.7% | 4 | 9.5% | .086 |
| yes | 29 | 76.3% | 38 | 90.5% | ||
| Loss of sexual desire | no | 15 | 39.5% | 14 | 33.3% | .568 |
| yes | 23 | 60.5% | 28 | 66.7% | ||
| Trouble achieving orgasm | no | 23 | 60.5% | 21 | 50.0% | .345 |
| yes | 15 | 39.5% | 21 | 50.0% | ||
| Trouble with erections | no | 32 | 84.2% | 35 | 83.3% | .915 |
| yes | 6 | 15.8% | 7 | 16.7% | ||
| Anxiety | no | 2 | 5.3% | 6 | 14.3% | .179 |
| yes | 36 | 94.7% | 36 | 85.7% | ||
| Poor concentration | no | 4 | 10.5% | 6 | 14.3% | .612 |
| yes | 34 | 89.5% | 36 | 85.7% | ||
| General malaise | no | 12 | 31.6% | 12 | 28.6% | .769 |
| yes | 26 | 68.4% | 30 | 71.4% | ||
| Restlessness | no | 2 | 5.3% | 10 | 23.8% | .020 |
| yes | 36 | 94.7% | 32 | 76.2% | ||
| Fatigue | no | 3 | 7.9% | 5 | 11.9% | .550 |
| yes | 35 | 92.1% | 37 | 88.1% | ||
| Decreased energy | no | 3 | 7.9% | 3 | 7.1% | .899 |
| yes | 35 | 92.1% | 39 | 92.9% | ||
| Other (specify) | no | 27 | 71.1% | 27 | 64.3% | .519 |
| yes | 11 | 28.9% | 15 | 35.7% | ||