Table 3.
Factors associated with resolving AKI
| n = 236 | Univariate Cox regression (hazard ratio) | p value | Multivariate Cox regression (hazard ratio) | p value | ||
|---|---|---|---|---|---|---|
| HR | (95% CI) | HR | (95% CI) | |||
| Age, per 10 year increase | 0.94 | 0.86–1.03 | 0.19 | |||
| Female gender | 0.85 | 0.61–1.17 | 0.31 | |||
| White race | 1.03 | 0.70–1.51 | 0.88 | |||
| Hispanic or Latino ethnic group | 1.50 | 0.98–2.30 | 0.06 | |||
| BMI | 1.00 | 0.98–1.02 | 0.88 | |||
| Diabetes mellitus | 0.91 | 0.61–1.34 | 0.63 | |||
| History of hypertension | 0.91 | 0.65–1.26 | 0.55 | |||
| Platelet count | < 0.001 | 0.27 | ||||
| > 150 × 109/L | 1 | 1 | ||||
| < 150 × 109/L | 0.54 | 0.38–0.78 | 0.80 | 0.53–1.19 | ||
| Urine output | < 0.0001 | 0.01 | ||||
| > 0.5 mL/kg/h | 1 | 1 | ||||
| < 0.5 mL/kg/h | 0.31 | 0.20–0.47 | 0.53 | 0.32–0.87 | ||
| PaO2/FiO2 ratio | < 0.0001 | 0.001 | ||||
| > 200 | 1 | 1 | ||||
| < 200 | 0.52 | 0.38–0.71 | 0.59 | 0.44–0.81 | ||
| Creatinine mg/dl, per unit increase | 0.59 | 0.48–0.74 | < 0.0001 | 0.71 | 0.57–0.89 | 0.003 |
| Systolic BP, per 10 mm Hg increase | 1.15 | 1.05–1.25 | 0.002 | 1.09 | 0.99–1.20 | 0.07 |
| Vasopressor use | 0.46 | 0.32–0.67 | < 0.0001 | 0.91 | 0.59–1.41 | 0.68 |
Factors associated with resolving AKI, defined as an AKI duration of less than 7 days, analyzed by the proportional subdistribution hazards model proposed by Fine and Gray, with death as a competing risk. Two patients were excluded from the original population (n = 238) due to missing values
AKI acute kidney injury, BMI body mass index, BP blood pressure, PaO2/FiO2 ratio partial pressure arterial oxygen/fraction of inspired oxygen