Fig. 2.

Effects of aHSP70 on insulin sensitivity. a Blood glucose decreases in response to an ip injection of insulin showed increased sensitivity following intranasal administration of 10 or 40 μg of aHSP70 three times per week for 24 days. Repeated measures ANOVA showed that the time x group interaction was significant (p < 0.001) and that at 30 and 60 min, the 40 μg group was significantly lower than the 0 μg control group (*p < 0.05; **p < 0.001). Means ± SEM of six mice per group. b Insulin level reductions were significantly correlated with aHSP70 dose