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| Outcome | First-line cytotoxic chemotherapy (n=124) | Overall | p value | |
|---|---|---|---|---|
| Pemetrexed-based (n=47) | Non-pemetrexed-based (n=77) | |||
| ORR+, n (%) | 21 (44.7) | 11 (14.3) | 32 (25.8) | <0.001 |
| ORR−, n (%) | 26 (55.3) | 66 (85.7) | 92 (74.2) | |
| DCR+, n (%) | 40 (85.1) | 48 (62.3) | 88 (71.0) | 0.008 |
| DCR−, n (%) | 7 (14.9) | 29 (37.7) | 36 (29.0) | |
ORR, objective response rate; DCR, disease control rate.
