Figure 2.

Inhibition by citalopram under static conditions of platelet adhesion to Horm collagen, CRP, fibrinogen and GFOGER. BSA and GPP were used as negative controls. Full concentration-inhibition curves were obtained for (RS)-, (R)- and (S)-citalopram (0–300 µM) for each ligand. 3-way ANOVA was performed with IBM SPSS v.23 (Effect 1 (fixed) = citalopram preparation {(RS), (R), (S)}; Effect 2 (fixed) = ligand {collagen, CRP, fibrinogen, GFOGER}; Effect 3 (random) = donor {N = 8–9 (RS) and N = 4 (R), (S)}). The results indicated no difference in the pIC₅₀ of the three citalopram preparations (P = 0.32, F = 1.18, df = 2, 44. H₀: μ_RS = μ_R = μ_S; H₁: μ_RS ≠ μ_R ≠ μ_S).