REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Anti-His (C-term) Antibody	Invitrogen	#P/N 46-0693
Bacterial and Virus Strains
Escherichia coli ATCC23724	ATCC	ATCC23724
Enterobacter cloacae	H. Monteil lab (University Louis Pasteur, Strasbourg)	N/A
Staphylococcus aureus RN6390	H. Monteil lab (University Louis Pasteur, Strasbourg)	N/A
Serratia marcescens Db11 20C2	Nehme et al., 2007	20C2
Bacillus subtilis	J. Millet lab (Pasteur institute of Paris)	N/A
Erwinia carotovora Ecc15	Basset et al., 2000	N/A
Enterococcus faecalis OG1RF	E. Murray lab (University of Texas) Kawalec et al., 2005	TX4002
E. faecalis gelE-	E. Murray lab (University of Texas) Kawalec et al., 2005	TX5264
E. faecalis sprE-	E. Murray lab (University of Texas) Kawalec et al., 2005	TX5243
E. faecalis gelE- and sprE-	E. Murray lab (University of Texas) Kawalec et al., 2005	TX5128
Enterococcus faecium	E. Murray lab (University of Texas) Kawalec et al., 2005	N/A
Pseudomonas aeruginosa PA14	F.M. Ausubel lab; Liberati et al., 2006	N/A
Pseudomonas aeruginosa; Elastase null mutant	F.M. Ausubel lab; Liberati et al., 2006	ID31939
Pseudomonas aeruginosa; Protease IV null mutant	F.M. Ausubel lab; Liberati et al., 2006	ID37740
Pseudomonas entomophila	B. Lemaitre lab (University of Lausanne)	N/A
Micrococcus luteus ATCC4698	ATCC	ATCC4698
Lactobacillus plantarum	W.J. Lee lab (Seoul National University)	N/A
Beauveria Bassiana 80.2	Gottar et al., 2006	N/A
Metarhizium anisopliae V275	Gottar et al., 2006	N/A
Candida glabrata	Gottar et al., 2006	N/A
Candida albicans	Isolated by M. Koenig (CHU Strasbourg-Hautepierre)	N/A
Chemicals, Peptides, and Recombinant Proteins
rpro-PshWT	This paper	N/A
rpro-PshM1	This paper	N/A
rpro-PshM2	This paper	N/A
rpro-Psh Ser339/Ala	This paper	N/A
rpro-Psh His144/Glu	This paper	N/A
rpro-Psh His144/Glu: Ser339/Ala	This paper	N/A
Protease, from Bacillus Sp.	Sigma	#P5985
Protease, from Aspergillus oryzae	Sigma	#P6110
Peptidoglycan from Micrococcus luteus	Sigma	#53243
Pepsine from porcine gastric mucosa	Sigma	#P6887
Azo dye-impregnated collagen	Sigma	#A4341
Z-Arg-MCA	Sigma-aldrich	#C8022
Z-Phe-Arg-AMC	Bachem	l-1160
(N-succinimidyloxycarbonyl-methyl)tris-(2,4,6-trimethoxyphenyl)phosphonium bromide (TMPP)	Ayoub et al., 2015	N/A
Porcine trypsin	Promega	#V5111
Deposited Data
Images of gels and blots	Mendeley data	https://doi.org/10.17632/mzgnrcftzv.1
Experimental Models: Cell Lines
Drosophila S2 cells	Invitrogen	#R69007
Experimental Models: Organisms/Strains
D. melanogaster w1118	El Chamy et al., 2008	N/A
D. melanogaster psh1	El Chamy et al., 2008	N/A
D. melanogaster grasshrd	El Chamy et al., 2008	N/A
D. melanogaster spzrm7	El Chamy et al., 2008	N/A
D. melanogaster C564-gal4 driver	Bloomington stock center	#6982
D. melanogaster 26-29-pKG00154	Bloomington stock center	#13051
D. melanogaster 26-29-pH3	This paper	N/A
D. melanogaster 26-29-pH6	This paper	N/A
D. melanogaster 26-29-pA2	This paper	N/A
D. melanogaster UAS-pro-PshWT	This paper	N/A
D. melanogaster UAS-pro-PshM1	This paper	N/A
D. melanogaster UAS-pro-PshM2	This paper	N/A
D. melanogaster ATT-3B VK00033	Bloomington stock center	#24871
P(SUPor-P)26-29-pKG00154	Bloomington stock center	#13051
P(TRIP.HMS00725)attP2	Bloomington stock center	#32932
P(TRIP.HMS02491)attP2	Bloomington stock center	#42655
P(TRIP.HMS00910)attP2	Bloomington stock center	#33955
Mi(MIC)CG11459MI08810	Bloomington stock center	#50488
P(EPgy2)CtsB1EY03339	Bloomington stock center	#15434
P(TRIP.GL00551)attP2	Bloomington stock center	#36591
P(SUPor-P)CG1440KG04580	Bloomington stock center	#13977
Recombinant DNA
pMT/V5-His vector	Invitrogen	#V412020
pJM1345: rpro-PshWT in pMT/V5-His	this paper	N/A
pJM1681: rpro-PshM1 in pMT/V5-His	this paper	N/A
pJM1682: rpro-PshM2 in pMT/V5-His	this paper	N/A
pUAST-attB vector	Bischof et al., 2007	N/A
pJM1692: pro-PshWT in pUAST-attB	this paper	N/A
pJM1693: pro-PshM1 in pUAST-attB	this paper	N/A
pJM1694: pro-PshM2 in pUAST-attB	this paper	N/A
pJM1674: rpro-Psh Ser339/Ala in pMT/V5-His	this paper	N/A
pJM1675: rpro-Psh His144/Glu in pMT/V5-His	this paper	N/A
pJM1676: rpro-Psh His144/Glu: Ser339/Ala in pMT/V5-His	this paper	N/A
pJM1689: rpro-cathepsin 26-29-p in pMT/V5-His	this paper	N/A
Software and Algorithms
GraphPad Prism 05	GraphPad Software	N/A
Mascot algorithm v2.5.1	Matrix Science	N/A
Scaffold software	Proteome Software	N/A
OASIS online application	Yang et al., 2011	N/A